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R0654 Sigma-Aldrich

Reveromycin A

solid

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Antibiotics by Mechanism of Action,
Quality Level   200
biological source   Streptomyces sp.
InChI Key   ZESGNAJSBDILTB-OXVOKJAASA-N
form   solid
mol wt   660.79 g/mol
packaging   pkg of 100 μg
color   tan
solubility   DMF: soluble
  DMSO: soluble
  ethanol: soluble
  ethyl acetate: soluble
  methanol: soluble
  soluble
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   fungi
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

It is an epidermal growth factor (EGF) and eukaryotic cell growth inhibitor.

Reveromycin A is a polyketide antibiotic from Streptomyces sp. Epidermal growth factor (EGF) inhibitor; apoptosis inducer; G1 phase cell cycle inhibitor having antiproliferative behavior against human cell lines KB and K562 as well as antifungal activity.

Analysis Note

Avoid acidic conditions.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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