• USA Home
  • R0900 - Anti-RANK (TRANCE-R) antibody produced in goat

R0900 Sigma

Anti-RANK (TRANCE-R) antibody produced in goat

affinity isolated antibody, lyophilized powder



Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   mouse
application(s)   indirect ELISA: 0.5-1.0 μg/mL
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Tnfrsf11a(21934)
biological source   goat
conjugate   unconjugated



recombinant mouse RANK extracellular domain expressed in Sf 21 insect cells.

General description

RANK also refers as TRANCE receptor (TRANCE R) or osteoclast differentiation factor (ODFR) is a receptor activator of NF-κB that belongs to the tumor necrosis factor receptor (TNFR) family. It is extensively expressed in skeletal muscle, small intestine, liver, colon, thymus and adrenal gland. It facilitates several biological functions like activating NF-κB and c-jun N-terminal kinase, enhancing T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. RANK (receptor activator of NF-κB) along with RANK ligand (RANKL) assists in regulation of interactions between T cells and dendritic cells. Anti-RANK (TRANCE-R) antibody can be used in indirect ELISA. Goat anti-RANK (TRANCE-R) antibody reacts specifically with recombinant mouse RANK. The product has also shown 20% cross-reactivity with recombinant human RANK.

Physical form

Lyophilized from a 0.2 μm-filtered solution in phosphate buffered saline with 5% trehalose.


Binding of antibody to cell surface RANK can trigger signal transduction and induce RANK-mediated bioactivity. By ELISA, the antibody shows 20% cross-reactivity with recombinant human RANK.


Anti-RANK (TRANCE-R) antibody can be used in western blotting (0.1-0.2 mug/mL).

Price and Availability

Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?