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R103 Sigma

Ritanserin

powder

Synonym: 6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

  • CAS Number 87051-43-2

  • Empirical Formula (Hill Notation) C27H25F2N3OS

  • Molecular Weight 477.57

  •  MDL number MFCD00069341

  •  PubChem Substance ID 24278117

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
InChI Key   JUQLTPCYUFPYKE-UHFFFAOYSA-N
form   powder
color   white
solubility   methanol: >10 mg/mL
  DMSO: >10.1 mg/mL
  2-hydroxypropyl-β-cyclodextrin: insoluble
  H2O: insoluble
  dilute aqueous base: insoluble
Gene Information   human ... HTR2A(3356)
rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)

Description

Packaging

25, 100, 250 mg in glass bottle

Biochem/physiol Actions

Potent 5-HT2A serotonin receptor antagonist/inverse agonist that crosses the blood-brain barrier.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R103.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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