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R9032 Sigma-Aldrich

R-715 TFA salt

≥95% (HPLC)

Synonym: Ac-Lys-[D-betaNal7,lle8]desArg9-bradykinin

  • Empirical Formula (Hill Notation) C57H81N13O12 · xC2HF3O2

  • Molecular Weight 1140.33 (free base basis)

  •  MDL number MFCD16875429

  •  PubChem Substance ID 329824043

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Bradykinins, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
color   white to off-white
solubility   H2O: >1 mg/mL
storage temp.   −20°C
SMILES string   OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccccc3)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(C)=O)C(O)=O
InChI   1S/C57H81N13O12.C2HF3O2/c1-4-34(2)48(56(81)82)68-51(76)43(31-37-23-24-38-17-8-9-18-39(38)29-37)66-52(77)44(33-71)67-50(75)42(30-36-15-6-5-7-16-36)64-47(73)32-62-53(78)45-21-13-27-69(45)55(80)46-22-14-28-70(46)54(79)41(20-12-26-61-57(59)60)65-49(74)40(63-35(3)72)19-10-11-25-58;3-2(4,5)1(6)7/h5-9,15-18,23-24,29,34,40-46,48,71H,4,10-14,19-22,25-28,30-33,58H2,1-3H3,(H,62,78)(H,63,72)(H,64,73)(H,65,74)(H,66,77)(H,67,75)(H,68,76)(H,81,82)(H4,59,60,61);(H,6,7)/t34-,40-,41-,42-,43+,44-,45-,46-,48-;/m0./s1
InChI key   ZFUJDXXJCMFOSK-WBUMRSSGSA-N

Description

Amino Acid Sequence

Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Ile

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Novel, selective, metabolically stable B1 bradykinin receptor antagonist.

Features and Benefits

This compound is featured on the Bradykinin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Bradykinin Receptors

The nonapeptide bradykinin (BK) and Lys-BK (kallidin) are naturally occurring substances produced in most species by the proteolytic digestion of high or low molecular weight kininogen by plasma and ...
Keywords: Angiogenesis, Atomic absorption spectroscopy, Cloning, Diabetes, Digestions, Gene expression, Growth factors, Inflammation, Ligands, Pharmacological actions, Transduction

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