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RAB1365 Sigma-Aldrich

Human CHL-1 ELISA

for serum, plasma and cell culture supernatants

  •  NACRES NA.32

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Properties

Related Categories Antibodies, Antibody Kits, ELISA Kits, Sandwich ELISAs
species reactivity   human
application(s)   ELISA: suitable
input   sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range   inter-assay cv: <12%
intra-assay cv: <10%
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... CHL1(10752)

Description

General description

CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.

This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells. CHL1 acts as a tumor-suppressor gene in breast cancer (BC). Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS). It participates in mental development.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Warning
Hazard statements 
RIDADR 
UN 3264 8 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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