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RES0196M-B7 Sigma

MOPSO

PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture

Synonym: β-Hydroxy-4-morpholinepropanesulfonic acid, 3-Morpholino-2-hydroxypropanesulfonic acid, MOPSO

  • CAS Number 68399-77-9

  • Empirical Formula (Hill Notation) C7H15NO5S

  • Molecular Weight 225.26

  •  Beilstein Registry Number 1109697

  •  EC Number 269-989-6

  •  MDL number MFCD00009629

  •  PubChem Substance ID 329824238

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Good’s Buffers, PharmaGrade Buffers
Quality Level   ELITE
biological source   synthetic
grade   Non-Compendial
InChI Key   NUFBIAUZAMHTSP-UHFFFAOYSA-N
product line   PharmaGrade
form   powder
useful pH range   6.2 - 7.6
pKa    6.9
suitability   suitable for cell culture
  suitable for manufacturing use
foreign activity   Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Description

Application

MOPSO is a biological buffer also referred to as a second generation “Good′s” buffer which displays improved solubility compared to traditional “Good′s” buffers. The pKa of MOPSO is 6.9 which make it an ideal candidate for buffer formulations which require a pH slightly below physiological to maintain a stable environment in solution. MOPSO is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPSO can be used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents.

Caution

According to Ferreira, et al., MOPSO can have a strong interaction with iron in solution. Based on this citation, it is recommended to use plastic-coated or PTFE-coated utensils when working with this chemical.

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Linkage

Enhanced Quality Product Documentation on PharmaGrade MOPSO

Packaging

Product is available in the following package sizes:
RES0196M-B701X: 100 gm container
RES0196M-B702X: 1 kg container
RES0196M-B704X: 10 kg container

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

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Peer-Reviewed Papers
15

References

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