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RES0199M-A7 SAFC

MOPSO, sodium salt

PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture

Synonym: 3-(N-Morpholinyl)-2-hydroxypropanesulfonic acid sodium salt, 3-Morpholino-2-hydroxypropanesulfonic acid sodium salt, MOPSO sodium salt

  • CAS Number 79803-73-9

  • Empirical Formula (Hill Notation) C7H14NNaO5S

  • Molecular Weight 247.24

  •  Beilstein/REAXYS Number 9448952

  •  MDL number MFCD00070007

  •  PubChem Substance ID 329824240

  •  NACRES NA.21

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Good’s Buffers, PharmaGrade Buffers
Quality Level   400
biological source   synthetic
Agency/Method   non-compendial
product line   PharmaGrade
form   powder
application(s)   cell culture | mammalian: suitable
useful pH range   6.2 - 7.6
pKa (25 °C)   6.9
suitability   suitable for manufacturing use
foreign activity   Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
SMILES string   [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
InChI   1S/C7H15NO5S.Na/c9-7(6-14(10,11)12)5-8-1-3-13-4-2-8;/h7,9H,1-6H2,(H,10,11,12);/q;+1/p-1
InChI key   WSFQLUVWDKCYSW-UHFFFAOYSA-M

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Application

MOPSO Sodium is a biological buffer also referred to as a second generation “Good′s” buffer which displays improved solubility compared to traditional “Good′s” buffers. The pKa of MOPSO Sodium is 6.9 which make it an ideal candidate for buffer formulations which require a pH slightly below physiological to maintain a stable environment in solution. MOPSO Sodium is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPSO Sodium can be used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MOPSO based buffers have been described for fixation of cells from urine samples.

Packaging

Product is available in the following package sizes:
RES0199M-A701X: 100 gm container
RES0199M-A702X: 1 kg container
RES0199M-A704X: 10 kg container

Caution

According to Ferreira, et al., MOPSO can have a strong interaction with iron in solution. Based on this citation, it is recommended to use plastic-coated or PTFE-coated utensils when working with this chemical.

Linkage

Enhanced Quality Product Documentation on PharmaGrade MOPSO, Sodium Salt

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

pHast Pack
Protocols & Articles

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Peer-Reviewed Papers
15

References

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