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RES1299C-B7 Sigma

CHES

PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture

Synonym: 2-(Cyclohexylamino)ethanesulfonic acid, CHES

  • CAS Number 103-47-9

  • Empirical Formula (Hill Notation) C8H17NO3S

  • Molecular Weight 207.29

  •  Beilstein Registry Number 2967601

  •  EC Number 203-115-6

  •  MDL number MFCD00003835

  •  PubChem Substance ID 329824255

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Good’s Buffers, PharmaGrade Buffers
Quality Level   ELITE
biological source   synthetic
grade   Non-Compendial
InChI Key   MKWKNSIESPFAQN-UHFFFAOYSA-N
product line   PharmaGrade
form   powder
impurities   Endotoxin, microbial, and trace metals; tested
useful pH range   8.6 - 10.0
pKa (25 °C)   9.3
suitability   suitable for cell culture
  suitable for manufacturing use
foreign activity   Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Description

Application

CHES is a biological buffer often referred to as a “Good’s” buffer. The pKa of CHES is 9.3, which makes CHES a good candidate for biological applications that require pH control above physiological. CHES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

CHES can be used in biological applications including as a component in media formulations. Specific applications include buffers for protein purification, bioprocessing and diagnostic reagent production.

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Linkage

Enhanced Quality Product Documentation on PharmaGrade CHES

Packaging

Product is available in the following package sizes:
RES1299C-B701X: 100 gm container
RES1299C-B702X: 1 kg container
RES1299C-B704X: 10 kg container

Safety & Documentation

High Quality GMP-Buffers

Protein Stabilizer
Protocols & Articles

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Peer-Reviewed Papers
15

References

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