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RES6007H-A7 SAFC

HEPES sodium salt

PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture

Synonym: 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium salt, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) sodium salt

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Good’s Buffers, PharmaGrade Buffers
Quality Level   400
biological source   synthetic
grade   Non-Compendial
InChI Key   RDZTWEVXRGYCFV-UHFFFAOYSA-M
product line   PharmaGrade
form   powder
application(s)   cell culture | mammalian: suitable
impurities   Endotoxin, microbial, and trace metals; tested
useful pH range   6.8 - 8.2
pKa (25 °C)   7.5
suitability   suitable for manufacturing use
foreign activity   Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Application

HEPES Sodium is a biological buffer often referred to as a “Good’s” buffer. HEPES Sodium, used in conjunction with HEPES, is the most commonly used biological buffer formulation since the pKa of the buffer is 7.31 which corresponds to the physiological pH of 7.36. HEPES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

HEPES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagent formulations.

Packaging

The product is available in the following package sizes:
RES6007H-A701X: 100g container
RES6007H-A702X: 1kg container
RES6007H-A704X: 10kg container
RES6007H-A705X: 25kg container

Linkage

Enhanced Quality Product Documentation on PharmaGrade HEPES, Sodium Salt

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Single- & multi-channel pipettes from BRAND
Protocols & Articles

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Peer-Reviewed Papers
15

References

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