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S0532 Sigma-Aldrich

Strychnine

Synonym: (−)-Strychnine

  • CAS Number 57-24-9

  • Empirical Formula (Hill Notation) C21H22N2O2

  • Molecular Weight 334.41

  •  Beilstein Registry Number 52979

  •  EC Number 200-319-7

  •  MDL number MFCD00005941

  •  PubChem Substance ID 24899441

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Description

Biochem/physiol Actions

Convulsant; glycine receptor antagonist not associated with the NMDA receptor.

At low doses, strychnine is used for circulatory problems, gastrointestinal disorders and eye diseases.

Packaging

5, 10, 25, 100 g in glass bottle

Application

Strychnine has been used in antagonist profiling to characterize a novel nicotinic receptor in Aplysia neuroendocrine cells.

General description

Strychnine is a glycine receptor antagonist not associated with the N-methyl-D-aspartate (NMDA) receptor. It is an alkaloid extracted from Strychnos nux vomica seeds.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1692 - class 6.1 - PG 1 - Strychnine
WGK Germany 
3
RTECS 
WL2275000

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Protocols & Articles

Articles

HPLC Analysis of Alkaloids on Discovery® RP-AmideC16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Alkaloids on Discovery® RP-AmideC16
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Alkaloids on Discovery® Zr-PBD

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Alkaloids on Discovery® Zr-PBD
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Amides on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Amides on Discovery® RP-Amide C16
Keywords: Analgesics, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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