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S1198 Sigma-Aldrich

Sumatriptan succinate

≥98% (HPLC), solid

Synonym: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

  • CAS Number 103628-48-4

  • Empirical Formula (Hill Notation) C14H21N3O2S · C4H6O4

  • Molecular Weight 413.49

  •  MDL number MFCD00902856

  •  PubChem Substance ID 329824466

  •  NACRES NA.77

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Properties

Related Categories Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   white to beige
solubility   H2O: >20 mg/mL
originator   GlaxoSmithKline
SMILES string   OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI   1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
InChI key   PORMUFZNYQJOEI-UHFFFAOYSA-N
Gene Information   human ... HTR1B(3351), HTR1D(3352)

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT1 receptor agonist can be used to treat migraine.

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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