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S1270 Sigma-Aldrich

β-Sitosterol

synthetic, ≥95%

Synonym: α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24β-Ethylcholesterol, 5-Stigmasten-3β-ol, beta-Sitosterol

  • CAS Number 83-46-5

  • Empirical Formula (Hill Notation) C29H50O

  • Molecular Weight 414.71

  •  Beilstein Registry Number 1916165

  •  EC Number 201-480-6

  •  MDL number MFCD00003631

  •  PubChem Substance ID 24899468

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Description

Packaging

10, 25, 100 mg in glass bottle

Application

β-Sitosterol has been used:
• to study its ability to improve the suitability of two pollens
• as a standard in the determination of sterol purities
• as a standard in quantitative genetic analysis
• as a standard in the estimation of plant sterols

Biochem/physiol Actions

A phytosterol with structure very similar to cholesterol that exhibits estrogenic activity. Inhibits proliferation of human leukemia cells, with G2/M arrest, endoreduplication, and polymerization of α-tubulin and microtubules.

Increased β-sitosterol administration displaces cholesterol during absorption. This elevates fecal secretion. It is known to regulate intestinal immunity.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
WJ2600000

Webinar - Hydrogels

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Protocols & Articles

Articles

BACSMLS Online Plate Map

BACSMLS compounds are conveniently provided at 5µg per well, enough for multiple injections. These are high purity (>95%) compounds supplied in an economical, ready to use format. Compounds are arran...
Keywords: Metabolites

Blocking Absorption of Dietary Cholesterol

Dietary cholesterol is obtained from foods derived from animal sources that are rich in fat content. A healthy adult only needs to ingest about 30% of the daily cholesterol requirement. Obtaining mor...
BioFiles 2007, 2.7, 9.
Keywords: Absorption, Biofiles

Peer-Reviewed Papers
15

References

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