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S1270 Sigma-Aldrich

β-Sitosterol

synthetic, ≥95%

Synonym: α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol, beta-Sitosterol

  • CAS Number 83-46-5

  • Empirical Formula (Hill Notation) C29H50O

  • Molecular Weight 414.71

  •  Beilstein/REAXYS Number 1916165

  •  EC Number 201-480-6

  •  MDL number MFCD00003631

  •  PubChem Substance ID 24899468

  •  NACRES NA.77

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Properties

Related Categories Acacia, Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Armoracia rusticana (Horseradish),
biological source   synthetic
assay   ≥95%
form   powder
mp   136-140 °C (lit.)
functional group   hydroxyl
shipped in   ambient
storage temp.   −20°C
SMILES string   [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@@H](CC)C(C)C
InChI   1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
InChI key   KZJWDPNRJALLNS-VJSFXXLFSA-N

Description

Application

β-Sitosterol has been used:
• to study its ability to improve the suitability of two pollens
• as a standard in the determination of sterol purities
• as a standard in quantitative genetic analysis
• as a standard in the estimation of plant sterols

Packaging

10, 25, 100 mg in glass bottle

Biochem/physiol Actions

A phytosterol with structure very similar to cholesterol that exhibits estrogenic activity. Inhibits proliferation of human leukemia cells, with G2/M arrest, endoreduplication, and polymerization of α-tubulin and microtubules.

Increased β-sitosterol administration displaces cholesterol during absorption. This elevates fecal secretion. It is known to regulate intestinal immunity.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
WJ2600000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

BACSMLS Online Plate Map

BACSMLS compounds are conveniently provided at 5µg per well, enough for multiple injections. These are high purity (>95%) compounds supplied in an economical, ready to use format. Compounds are arran...
Keywords: Metabolites

Blocking Absorption of Dietary Cholesterol

Dietary cholesterol is obtained from foods derived from animal sources that are rich in fat content. A healthy adult only needs to ingest about 30% of the daily cholesterol requirement. Obtaining mor...
BioFiles 2007, 2.7, 9.
Keywords: Absorption, Biofiles

Peer-Reviewed Papers
15

References

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