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  • S1300 - Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

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S1300 Sigma-Aldrich

Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

2 mg/mL, clone FMC46, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-L-Selectin, Monoclonal Anti-CD62L

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
conjugate   unconjugated
clone   FMC46, monoclonal
biological source   mouse
application(s)   flow cytometry: suitable
  immunohistochemistry (frozen sections): suitable
species reactivity   human
mol wt   antigen 74-95 kDa
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG2b
antibody product type   primary antibodies
concentration   2 mg/mL
UniProt accession no.   P14151
Gene Information   human ... SELL(6402)

Description

Specificity

Recognizes the CD62L (L-Selectin, LAM-1, Leu8, TQ1, LECAM-1, LECCAM-1, DREG) surface antigen. The antibody recognizes an epitope localized to the lectin domain. It inhibits "rolling" interactions and significantly reduces the binding of FITC-yeast phosphomannan monoester core polysaccharide to lymphocytes, monocytes and neutrophils.
5th Workshop: Code No. S061

Immunogen

human PHA-activated peripheral blood mononuclear cells.

Target description

CD62L, a glycoprotein and member of the selectin family of adhesion receptors, is constitutively expressed on all classes of leukocytes including lymphocytes, monocytes, and polymorphonuclear cells. It is expressed on myeloid progenitor cells, erythroid precursor cells, and some thymocytes.

Physical form

Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

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