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S1450 Sigma-Aldrich

Anti-Superoxide Dismutase (MnSOD) (DD-17)−Cy3 antibody produced in rabbit

1-2 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Indophenoloxidase B, Anti-IPO-B, Anti-MNSOD, Anti-Manganese Superoxide Dismutase 2, Anti-Manganese dependent SOD, Anti-Mitochondrial SOD, Anti-SOD2, Anti-Superoxide dismutase 2

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Cell Stress, Antibodies to Oxidative Stress Proteins,
conjugate   CY3 conjugate
clone   polyclonal
biological source   rabbit
application(s)   direct immunofluorescence: 2-5 μg/mL using human HeLa, rat NRK and mouse 3T3 cells.
species reactivity   rat, human, mouse
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
packaging   antibody small pack of 25 μL
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
concentration   1-2 mg/mL
UniProt accession no.   P04179
Gene Information   human ... SOD2(6648)

Description

General description

The SOD2 (superoxide dismutase 2) gene is mapped to human chromosome 6q25.3. The encoded protein functions as a tetramer and is localized to mitochondria.

Immunogen

synthetic peptide corresponding to amino acid residues 183-199 of human superoxide dismutase (MnSOD), conjugated to KLH. The corresponding sequence is conserved in many eukaryotes.

Application

Anti-Superoxide Dismutase (MnSOD) (DD-17)-Cy3 antibody produced in rabbit has been used in immunohistochemistry.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Superoxide dismutase 2 (SOD2) is an antioxidant enzyme and catalyzes the conversion of superoxide to hydrogen peroxide and molecular oxygen. The enzyme offers protection against oxidative damage induced by reactive oxygen species and is also radioprotective. The gene is associated with the metastasis and invasion process of salivary adenoid cystic carcinoma. Manganese SOD is involved in detoxification.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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S5069 Anti-Superoxide Dismutase (MnSOD) (DD-17) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

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