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S166 Sigma-Aldrich

Saclofen

solid

Synonym: β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid

  • CAS Number 125464-42-8

  • Empirical Formula (Hill Notation) C9H12ClNO3S

  • Molecular Weight 249.71

  •  MDL number MFCD00216817

  •  PubChem Substance ID 329824485

  •  NACRES NA.32

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Properties

Related Categories Antagonists, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GABAergics,
Quality Level   200
form   solid
color   white
solubility   0.1 M NaOH: 20 mg/mL
SMILES string   NCC(CS(O)(=O)=O)c1ccc(Cl)cc1
InChI   1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
InChI key   JYLNVJYYQQXNEK-UHFFFAOYSA-N
Gene Information   human ... GABBR1(2550), GABBR2(9568)
mouse ... GABBR1(54393), GABBR2(242425)
rat ... GABBR1(81657), GABBR2(83633)

Description

Application

Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.

Packaging

5 mg in glass bottle

Biochem/physiol Actions

Saclofen is the sulphonic analog of baclofen and is a selective GABAB receptor antagonist.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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