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S2068 Sigma-Aldrich

Salvinorin A

solid, ≥98% (HPLC)

Synonym: (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester

  • CAS Number 83729-01-5

  • Empirical Formula (Hill Notation) C23H28O8

  • Molecular Weight 432.46

  •  MDL number MFCD05664742

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Properties

InChI Key   OBSYBRPAKCASQB-AGQYDFLVSA-N
assay   ≥98% (HPLC)
form   solid
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
color   white
solubility   DMSO: 10 mg/mL
  ethanol: 3 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

Other Notes

Salvinorin A has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the Salvinorin A probe summary on the Chemical Probes Portal website.

Safety & Documentation

Safety Information

WGK Germany 
3
RTECS 
QL6127142

Documents

Certificate of Analysis (COA)

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