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S2501 Sigma-Aldrich

Spermidine trihydrochloride

≥98% (TLC)

Synonym: N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

  • CAS Number 334-50-9

  • Linear Formula NH2(CH2)3NH(CH2)4NH2 · 3HCl

  • Molecular Weight 254.63

  •  Beilstein/REAXYS Number 3552356

  •  EC Number 206-379-0

  •  MDL number MFCD00012918

  •  PubChem Substance ID 24277993

  •  NACRES NA.32

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Properties

Related Categories Amino Acid, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes,
Quality Level   200
biological source   microbial
  synthetic
assay   ≥98% (TLC)
form   powder
mp   257-259 °C (lit.)
solubility   water: 100 mg/mL, clear, colorless
storage temp.   room temp
SMILES string   Cl[H].Cl[H].Cl[H].NCCCCNCCCN
InChI   1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
InChI key   LCNBIHVSOPXFMR-UHFFFAOYSA-N
Gene Information   human ... NOS1(4842)

Description

General description

The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.

Application

Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.

Packaging

1, 5, 25 g in poly bottle

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Caution

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
EJ7023000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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