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S3147 Sigma

5-Sulfosalicylic acid dihydrate

for electrophoresis, ≥99%

Synonym: 2-Hydroxy-5-sulfobenzoic acid

  • CAS Number 5965-83-3

  • Linear Formula HO3SC6H3-2-(OH)CO2H·2H2O

  • Molecular Weight 254.21

  •  Beilstein Registry Number 650741

  •  EC Number 202-555-6

  •  MDL number MFCD00149540

  •  PubChem Substance ID 24899547

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Properties

Related Categories Biochemicals and Reagents, Chelators, Molecular Biology, Protein Electrophoresis, Proteomics,
grade   for electrophoresis
InChI Key   BHDKTFQBRFWJKR-UHFFFAOYSA-N
assay   ≥99%
impurities   ≤0.02% Insoluble matter
  ≤0.05% Salicylic Acid
mp   105-110 °C (lit.)
solubility   water: soluble 100 mg/mL, clear, colorless
anion traces   chloride (Cl-): ≤0.001%
  sulfate (SO42-): ≤0.02%
cation traces   Fe: ≤0.001%
  heavy metals (as Pb): ≤0.002%

Description

Analysis Note

Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.

Packaging

100, 500 g in poly bottle

Application

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].

General description

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
1
Protocols & Articles
Peer-Reviewed Papers
15

References

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