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S3523 Sigma-Aldrich

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

  • CAS Number 24730-31-2

  • Empirical Formula (Hill Notation) C53H93N7O13

  • Molecular Weight 1036.34

  •  PubChem Substance ID 24899562

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action, Antifungal,
biological source   Bacillus subtilis
description   zwitterionic
InChI Key   NJGWOFRZMQRKHT-WGVNQGGSSA-N
assay   ≥98.0% (HPLC)
form   powder
color   white to faint yellow
CMC   7.5-20 μmol/L (depending on methods)
solubility   ethanol: soluble 10 mg/mL
Mode of action   cell membrane | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  fungi
  mycoplasma
  neoplastics
  viruses
storage temp.   2-8°C

Description

General description

Chemical structure: peptide

Application

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Packaging

10, 50 mg in poly bottle

Biochem/physiol Actions

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
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