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S5319 Sigma-Aldrich

Sodium Stibogluconate

≥98% (titration), solid

Synonym: 2,4:2′,4′-O-(Oxy-distibylidyne)bis[D-gluconic acid] Sb,Sb-dioxide trisodium salt

  • CAS Number 16037-91-5

  • Empirical Formula (Hill Notation) C12H17O17Sb2 ·3Na

  • Molecular Weight 745.74

  •  MDL number MFCD06795860

  •  PubChem Substance ID 24724613

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Properties

assay   ≥98% (titration)
form   solid
storage condition   desiccated
  protect from light
  under inert gas
color   pale yellow
solubility   H2O: 1 mg/mL at ~75 °C
storage temp.   2-8°C

Description

Biochem/physiol Actions

Irreversibly inhibits protein tyrosine phosphatase (SHP-1) activity (99% inhibition at 11μM). Inhibits SHP-2 and PTP1B at 10-folds higher concentration. Induces general tyrosine phosphorylation. Augments IL-3-induced proliferation in Baf3 cells (Emax=55 μM).

Packaging

Package under nitrogen, protected from light with a desiccant.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
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