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  • S8809 - Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse

S8809 Sigma-Aldrich

Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse

~1 mg/mL, clone K58/35, purified immunoglobulin



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Ion Channels, Antibodies to Sodium Channels,
conjugate   unconjugated
clone   K58/35, monoclonal
biological source   mouse
application(s)   immunohistochemistry (frozen sections): suitable
  indirect immunofluorescence: 1 μg/mL using sciatic and optic nerve sections; cultured hypocampal neurons
  western blot: 1 μg/mL using crude brain membrane prep (rat)
species reactivity   mammals
shipped in   wet ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG1
Quality Level   200
antibody product type   primary antibodies
concentration   ~1 mg/mL
UniProt accession no.   P35498
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN8A(6334), SCN9A(6335)
mouse ... Scn10a(20264), Scn11a(24046), Scn1a(20265), Scn3a(20269), Scn4a(110880), Scn5a(20271), Scn8a(20273), Scn9a(20274)
rat ... Scn10a(29571), Scn11a(29701), Scn1a(81574), Scn3a(497770), Scn4a(25722), Scn5a(25665), Scn8a(29710), Scn9a(78956)



The sequence recognized by this clone is identical in all known vertebrate Na+ channels. In cultured hippocampal neurons, the antibody specifically stains the axon initial segment. In sciatic and optic nerves, it stains the nodes of Ranvier.


synthetic peptide CTEEQKKYYNAMKKLGSKK from the intracellular III-IV loop of Na+ channels

Physical form

Solution in 10 mM Tris, pH 7.5, containing 0.1 m NaCl, 30% glycerol, and 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Legal Information

Sold under exclusive license from SUNY Stony Brook.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Protocols & Articles


Antibody Basics

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