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  • SAB1300879 - Anti-RASGRF1 (S929) antibody produced in rabbit

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SAB1300879 Sigma-Aldrich

Anti-RASGRF1 (S929) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Apoptosis-stimulating of p53 protein 1, Anti-ASPP1, Anti-KIAA0771, Anti-PPP1R13B, Anti-Protein phosphatase 1 regulatory subunit 13B

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, Primary Antibodies, RAE-RAX
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry: 1:50-1:100
  indirect ELISA: 1:1000
species reactivity   human
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
NCBI accession no.   NP_002882
UniProt accession no.   Q13972
Gene Information   human ... RASGRF1(5923)

Description

General description

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Immunogen

RASGRF1 (NP_002882, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S929 of human RASGRF1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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