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  • SAB1300919 - Anti-PHLPP2 (N-term) antibody produced in rabbit

SAB1300919 Sigma-Aldrich

Anti-PHLPP2 (N-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Synonym: Anti-KIAA0931, Anti-PH domain leucine-rich repeat protein phosphatase-like, Anti-PHLPP-like, Anti-PHLPP2, Anti-PHLPPL



Related Categories Alphabetical Index, Antibodies, PH-PI, Primary Antibodies
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry: 1:50-1:100
  indirect ELISA: 1:1000
species reactivity   human
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   saturated ammonium sulfate (SAS) precipitated
antibody product type   primary antibodies
NCBI accession no.   NP_055835
UniProt accession no.   Q6ZVD8
Gene Information   human ... PHLPP2(23035)


General description

The PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) gene with 18 exons, is mapped to human chromosome 16q22.2. The encoded protein is a isoform of PHLPP family and is composed of 1323 amino acids. PHLPP2 is characterized with a pleckstrin homology domain (PH domain), leucine-rich repeats, a protein phosphatase 2C (PP2C) domain and a PDZ-binding motif.


PHLPP2 (NP_055835, 9-42)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human PHLPP2.


Anti-PHLPP2 (N-term) antibody produced in rabbit has been used in immunoblotting.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) is a tumor suppressor. It plays a vital role in cell survival by inactivating Akt, inhibiting cell-cycle progression and stimulating apoptosis. Expression of PHLPP protein is decreased in hypopharyngeal squamous cell carcinomas (HSCCs). Thus, this protein can be used as a marker to determine the poor prognosis in HSCCs patients.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Protocols & Articles


Antibody Basics

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