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  • SAB1400282 - Monoclonal Anti-TLN1 antibody produced in mouse

SAB1400282 Sigma

Monoclonal Anti-TLN1 antibody produced in mouse

clone 2E10, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-ILWEQ, Anti-KIAA1027, Anti-TLN



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Actin-associated Proteins/Myosin, Antibodies to Cell and Organelle Proteins,
species reactivity   mouse, human, rat
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect ELISA: suitable
  western blot: 1-5 μg/mL
clone   2E10, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG3κ
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TLN1(7094)
biological source   mouse
conjugate   unconjugated



TLN1 (NP_006280, 1052 a.a. ~ 1149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


General description

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. (provided by RefSeq)

Physical form

Solution in phosphate buffered saline, pH 7.4

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