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  • SAB1400574 - Anti-SPA17 antibody produced in mouse

SAB1400574 Sigma

Anti-SPA17 antibody produced in mouse

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-SP17-1, Anti-SP17



Related Categories Alphabetical Index, Antibodies, Primary Antibodies, SP-SS
species reactivity   human
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect immunofluorescence: suitable
  western blot: 1 μg/mL
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... SPA17(53340)
biological source   mouse
conjugate   unconjugated



SPA17 (NP_059121.1, 1 a.a. ~ 151 a.a) full-length human protein.


General description

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22

Physical form

Solution in phosphate buffered saline, pH 7.4

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Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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