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  • SAB1411371 - Anti-TXN antibody produced in rabbit

SAB1411371 Sigma-Aldrich

Anti-TXN antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

Synonym: DKFZp686B1993, MGC61975, TRX1, TRX

  •  NACRES NA.41



conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   western blot: 1 μg/mL
species reactivity   human
mol wt   antigen 11.7 kDa
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   purified immunoglobulin
Quality Level   100
antibody product type   primary antibodies
NCBI accession no.   NM_003329.2
UniProt accession no.   P10599
Gene Information   human ... TXN(7295)


General description

Thioredoxin (TXN) is a 12 kDa oxidoreductase enzyme containing a dithiol-disulfide active site, which is required for the redox regulatory function. It is widely expressed in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been recognized, including ribonuclease, choriogonadotropin, coagulation factors, glucocorticoid receptor and insulin. Reduction of insulin is classically used as an activity test. TXN is encoded by the gene mapped to human chromosome 9q31.


TXN (NP_003320.2, 1 a.a. ~ 105 a.a) full-length human protein.


Physical form

Solution in phosphate buffered saline, pH 7.4


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Thioredoxin (TXN) plays an important role in protecting cells against apoptosis under oxidative stress by enhancing the total antioxidant ability, reducing the reactive oxygen species (ROS) levels as well as by stabilizing the actin cytoskeletal system. It also plays an essential role in donating deoxyribonucleotides for DNA replication.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Antibody Basics

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Western Blot Protocol | Immunoblotting Protocol

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