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SAB2501553 Sigma-Aldrich

Anti-Itga11 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-4732459H24Rik, Anti-Itga11, Integrin a11, Integrin alpha-11

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, IQ-IZ, Primary Antibodies
conjugate   unconjugated
clone   polyclonal
biological source   goat
application(s)   indirect ELISA: suitable
  western blot: suitable
species reactivity   mouse, rat
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
UniProt accession no.   P61622
Gene Information   mouse ... Itga11(319480)

Description

General description

Integrin subunit α 11 (ITGA11) is expressed in stromal fibroblasts. Together with the integrin subunit β, it forms a receptor for collagen.

Immunogen

Peptide with sequence PTEEDLSHAPQRNH, from the internal region (near C-terminus) of the protein sequence according to NP_795896.4

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Biochem/physiol Actions

Integrin subunit α 11 (ITGA11) may have a role in the organization of interstitial collagen matrices. It has been shown to be upregulated in non-small-cell lung carcinoma. Mice, which are deficient in ITGA11, exhibit signs of dwarfism and malnutrition.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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