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SAB2702171 Sigma-Aldrich

Monoclonal Anti-PSMC5 antibody produced in mouse

Synonym: TBP10, TRIP1, p45/SUG, p45

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Properties

Related Categories Alphabetical Index, Antibodies, PS-PS, Primary Antibodies
conjugate   unconjugated
clone   25D5
  monoclonal
biological source   mouse
application(s)   western blot: 1:1000
species reactivity   human
mol wt   mol wt 45 kDa
form   liquid
shipped in   wet ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG
antibody product type   primary antibodies
concentration   1 mg/mL
UniProt accession no.   P62195
Gene Information   human ... PSMC5(5705)

Description

Immunogen

Recombinant protein encoding full-length SUG1 purified from E. coli.

Application

For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.

Physical form

Phosphate-buffered saline, pH 7.4, containing no preservatives

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Human PSMC5 (also known as SUG1, p45, Rpt6 and Cim3) is a component of the 19S regulatory subunit of the 26S proteosome complex. It is one of the AAA ATPas found in the 19S regulatory complex that is thought to participate in the unfolding of ubiquitinated proteins in an ATP-dependent manner. It has also been shown to directly interact with the nucleotide excision repair protein XPB.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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