• USA Home
  • SAB2900091 - Anti-SLC7A11 antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
SAB2900091 Sigma-Aldrich

Anti-SLC7A11 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: CCBR1, amino acid transport system xc-, calcium channel blocker resistance protein 1, cystine/glutamate transporter, solute carrier family 7 member 11

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies to Drug Transport Proteins, Biochemicals and Reagents, Drug Transport Proteins & Reagents,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
species reactivity   human
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
Quality Level   100
UniProt accession no.   Q9UPY5
Gene Information   human ... SLC7A11(23657)

Description

General description

Solute carrier family 7, membrane 11 (SLC7A11), a constituent of the cysteine-glutamate transporter, is located on human chromosome 4q28.31. It belongs to the system xc- light chain family. SLC7A11 gene codes for the cystine-glutamate antiporter Xct.

Immunogen

Synthetic 19 amino acid peptide from N-terminus of human SLC7A11. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Monkey, Marmoset (95%); Horse (89%); Rat, Dog, Hamster (84%).

Application

Anti-SLC7A11 antibody has been used in western blot analysis.

Physical form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Solute carrier family 7, membrane 11 (SLC7A11) or xCT participates in glutathione homeostasis, that helps to guard the cells against oxidative stress. It is involved in the pathogenesis of malignant tumors. SLC7A11 is associated with triple negative breast cancer and glioblastoma (GBM).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Related Content

Antibody Explorer | Buy Primary Antibodies & Secondary Antibodies

Primary, Secondary and Recombinant Monoclonal Antibodies Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay...
Keywords: Alzheimer Disease, Cancer, Chromatin immunoprecipitation, Diagnostic, Enzyme-linked immunosorbent assay, Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Neuroscience, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?