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  • SAB4100168 - Monoclonal Anti-PRKAR2A antibody produced in mouse

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SAB4100168 Sigma-Aldrich

Monoclonal Anti-PRKAR2A antibody produced in mouse

clone PRKAR2A-A181, culture supernatant

Synonym: Anti-PKR2, Anti-PRKAR2, Anti-Protein kinase A, RII-alpha subunit, Anti-Protein kinase, cAMP-dependent, regulatory, type II, alpha, Anti-Protein kinase, camp-dependent, regulatory, type II, α (PRKAR2A), Anti-cAMP-dependent protein kinase, regulatory subunit alpha 2

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, PR-PR, Primary Antibodies
conjugate   unconjugated
clone   PRKAR2A-A181, monoclonal
biological source   mouse
application(s)   western blot: suitable
species reactivity   human
mol wt   antigen predicted mol wt 45.3 kDa
form   aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   culture supernatant
antibody product type   primary antibodies
UniProt accession no.   P13861
Gene Information   human ... PRKAR2A(5576)

Description

General description

cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) is a regulatory subunit of a heterotetrametric protein, protein kinase A (PKA).. It exists as RIIα isoform of type II PKA. It is located on the human chromosome 3p21.3−p21.2.

Immunogen

PRKAR2A purified recombinant protein

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Biochem/physiol Actions

cAMP-dependent protein kinase type II-α regulatory subunit (PRKAR2A) mediates the sub-cellular association by interacting to specific A-kinase anchoring proteins. It plays a key role in cyclic adenosine monophosphate (cAMP) signaling in eukaryotic cells, regulation of metabolism and cell growth. It is implicated in the protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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