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  • SAB4200358 - Anti-PLAUR antibody produced in rabbit

SAB4200358 Sigma-Aldrich

Anti-PLAUR antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

Synonym: Anti-CD87, Anti-U-PAR, Anti-UPAR, Anti-URKR, Anti-Urokinase receptor, Anti-plasminogen activator

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cell and Organelle Proteins, Antibodies to Cytoskeleton,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   indirect immunofluorescence: 1-2 μg/mL using human HeLa cells.
  western blot: 0.5-1.0 μg/mL using whole extracts of HEK-293T cells over-expressing human PLAUR.
species reactivity   human
mol wt   antigen 45/50 kDa
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
concentration   ~1.0 mg/mL
UniProt accession no.   Q03405
Gene Information   human ... PLAUR(5329)


General description

Plasminogen activator urokinase receptor (PLAUR)/ urokinase plasminogen activator receptor (uPAR), a member of Ly6/ neurotoxin receptor family, is a heavily glycosylated glycosyl-phosphatidylinositol (GPI)-anchored cell-surface receptor. It is comprised of serine protease uPA, specific inhibitors (plasminogen activator inhibitors 1 and 2) and three internally disulfide-bonded domains (D1, D2 and D3).


peptide corresponding to a sequence at the C-terminus of human PLAUR, conjugated to KLH. The corresponding sequence is identical in monkey PLAUR.


Anti-PLAUR antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Plasminogen activator urokinase receptor (PLAUR)/ urokinase plasminogen activator receptor (uPAR) acts as a receptor for urokinase plasminogen activator (uPA). It localizes and promotes plasmin formation. uPAR influences many normal and pathological processes related to cell surface plasminogen activation, degradation of the extracellular matrix, cell migration, leukocyte adhesion, chemotaxis and signal transduction during leukocyte recruitment from the circulation to extravascular sites of inflammation. It is implicated as an anti-cancer target. uPAR is involved in epilepsy, language, cognition, communication and central nervous system disorders.

Safety & Documentation

Safety Information

NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

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Western Blot Protocol | Immunoblotting Protocol

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Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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