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  • SAB4200752 - Anti-Nuclease P1 antibody produced in rabbit

SAB4200752 Sigma-Aldrich

Anti-Nuclease P1 antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

Synonym: Anti-Deoxyribonuclease P1, Anti-Endonuclease P1

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, NS-NZ, Primary Antibodies
clone   polyclonal
biological source   rabbit
application(s)   immunoblotting: 1:10,000-1:20,000 using Nuclease P1 from Penicillium citrinum
mol wt   ~30 kDa
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   Ig fraction of antiserum
Quality Level   200
antibody product type   primary antibodies
concentration   ~1 mg/mL
UniProt accession no.   P24289


General description

Nuclease P1 (Nuclease 5′-Nucleotidehydrolase, 3′- Phosphohydrolase, EC, also known as deoxyribonuclease P1 or endonuclease P1, is a zinc dependent endonuclease. It is isolated from Penicillium citrinum.


Nuclease P1 from Penicillium citrinum


Anti-Nuclease P1 antibody produced in rabbit has been used in immunoblotting.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Biochem/physiol Actions

Nuclease P1 catalyzes the hydrolysis of 3′-5′ phosphodiester bonds in RNA and single-stranded DNA and 3′-phosphomonoester bonds in mono- and oligonucleotides terminated by a 3′-phosphate group without apparent bases specificity. The enzyme is used as a component of nuclease cocktail to generate single-stranded oligodeoxynucleotide (ODNs) samples for mass spectroscopy research for characterization of oligodeoxyribonucleotides. Nuclease P1 has also been widely used in the food industry to enhance or create flavor.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


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