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  • SAB4300105 - Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit

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SAB4300105 Sigma-Aldrich

Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit

affinity isolated antibody

Synonym: Anti-HDACL1 antibody produced in rabbit, Anti-RPD3 antibody produced in rabbit, Anti-histone deacetylase 8 antibody produced in rabbit

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Phosphoproteins at Phosphoserine (pSer),
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
  indirect immunofluorescence: 1:100-1:200
species reactivity   human
mol wt   ~42 kDa
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
isotype   IgG
Quality Level   100
antibody product type   primary antibodies
concentration   1 mg/mL
immunogen sequence   (R-A-SP-M-V)
NCBI accession no.   NP_001159890.1
UniProt accession no.   Q9BY41
Gene Information   human ... HDAC8(55869)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8.

Target description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

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