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SAB4500776 Sigma-Aldrich

Anti-EPHB1 antibody produced in rabbit

affinity isolated antibody

Synonym: ELK, EPB1, EPHT2, EPTH2, Eph receptor B1

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Properties

Related Categories Alphabetical Index, Antibodies, EO-ER, Primary Antibodies
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   ELISA: 1:20000
  immunofluorescence: 1:100-1:500
  immunohistochemistry: 1:50-1:100
species reactivity   mouse, human
mol wt   antigen 109 kDa
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
concentration   ~1 mg/mL
NCBI accession no.   P54762
UniProt accession no.   P54762
Gene Information   human ... EPHB1(2047)

Description

General description

Anti-EPHB1 Antibody detects endogenous levels of total EPHB1 protein.

EPHB1(ephrin type-B receptor 1) belongs to the Eph gene family of receptor tyrosine kinases. It is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human EPHB1/2/3.

Immunogen Range: 631-680

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). It plays a major role in the growth of nervous and vascular system. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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