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  • SAB4503020 - Anti-p53 (Acetyl-Lys386), C-Terminal antibody produced in rabbit

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SAB4503020 Sigma-Aldrich

Anti-p53 (Acetyl-Lys386), C-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym: Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

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Properties

Related Categories Alphabetical Index, Antibodies, Molecular Mechanisms of Cancer, P-PA, Pathway-Associated Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   ELISA: 1:40000
  immunofluorescence: 1:100-1:500
  immunohistochemistry: 1:50-1:100
species reactivity   human
mol wt   antigen mol wt 43 kDa
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
concentration   ~1 mg/mL
NCBI accession no.   P04637
UniProt accession no.   P04637
Gene Information   human ... TP53(7157)

Description

General description

Anti-p53 (Acetyl-Lys386) Antibody detects endogenous levels of total p53 (Acetyl-Lys386) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human p53 around the acetylated site of Lys386.

Immunogen Range: 344-393

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

p53: DNA Damage Response and Cancer

p53 is a transcription factor that binds to defined consensus sites within DNA. A major function of p53 is to repress genes involved in cell growth stimulation while activating alternate genes involv...
Keywords: Acetylations, Adhesion, Apoptosis, Cancer, Carcinogens, DNA replication, Degradations, Eliminations, Environmental, Gene expression, Phosphorylations, Substitutions, Transcription

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