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SAB5200078 Sigma-Aldrich

Monoclonal Anti-OLFM1 antibody produced in mouse

clone S96-7, 1 mg/mL, purified immunoglobulin

Synonym: Anti-AMY, Anti-Noe1, Anti-Noelin, Anti-Olfactomedin1, Anti-Olfm1, Anti-Pancortin, S96-7

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Properties

Related Categories Alphabetical Index, Antibodies, O, Primary Antibodies
conjugate   unconjugated
clone   S96-7, monoclonal
biological source   mouse
application(s)   immunohistochemistry: suitable
  immunoprecipitation (IP): suitable
  western blot: suitable
species reactivity   rat, human, mouse
mol wt   antigen predicted mol wt 70 kDa
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG1
Quality Level   100
antibody product type   primary antibodies
concentration   1 mg/mL
NCBI accession no.   NP_001033701.1
UniProt accession no.   Q99784
Gene Information   human ... Olfm1(10439)

Description

General description

Olfactomedin 1 (OLFM1) is localized to various organs like the heart, lungs and eyes. The gene encoding it is localized on human chromosome 9q34.3.

Specificity

Detects ~70 kDa (Pancortin-1, Pancortin-3) and ~20 kDa (Pancortin-2 and Pancortin-4).

Immunogen

Synthetic peptide of amino acids 28-48 of human pancortin-1 (SLVGLNTTRLSAASGGTLDRS), Accession Number Q99784.

Physical form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Biochem/physiol Actions

Olfactomedin 1 (OLFM1) is downregulated in the human endometrium. When it is upregulated, complications like endometriosis and ectopic pregnancy are observed. OLFM1 may act as a cell adhesion protein and it has been shown to modulate the Wnt-signaling pathway.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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