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SAB5500088 Sigma-Aldrich

Anti-CSF-1R antibody, Rabbit monoclonal

clone SP211, recombinant, expressed in proprietary host, affinity isolated antibody

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Properties

Related Categories Alphabetical Index, Antibodies, CS-CS, Primary Antibodies, Rabbit Monoclonal Antibodies,
conjugate   unconjugated
clone   SP211, monoclonal
biological source   rabbit
application(s)   immunohistochemistry: 1:100
species reactivity   human (tested)
species reactivity (predicted by homology)   mouse, rat
shipped in   wet ice
storage temp.   2-8°C
antibody form   affinity isolated antibody
isotype   IgG
antibody product type   primary antibodies
recombinant   expressed in proprietary host
UniProt accession no.   P07333
Gene Information   human ... CSF1R(1436)

Description

General description

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor and CD115, is a cell-surface tyrosine-protein kinase receptor for colony stimulating factor 1 (CSF1) and IL-34. It is expressed by monocytes and its progenitor or derived cells. It plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. It is up-regulated in some human tumors such as carcinoma of ovary and breast.

Immunogen

Synthetic peptide from human CSF-1R protein.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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