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SAB5500095 Sigma-Aldrich

Anti-EPHA2 antibody, Rabbit monoclonal

clone SP169, recombinant, expressed in proprietary host, affinity isolated antibody

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Properties

Related Categories Alphabetical Index, Antibodies, EO-ER, Primary Antibodies, Rabbit Monoclonal Antibodies,
conjugate   unconjugated
clone   SP169, monoclonal
biological source   rabbit
application(s)   flow cytometry: 1:100
  immunohistochemistry: 1:100
species reactivity   human (tested)
species reactivity (predicted by homology)   mouse, monkey
shipped in   wet ice
storage temp.   2-8°C
antibody form   affinity isolated antibody
isotype   IgG
antibody product type   primary antibodies
recombinant   expressed in proprietary host
UniProt accession no.   P29317
Gene Information   human ... EPHA2(1969)

Description

General description

Ephrin type-A receptor 2 (EphA2) is a protein-tyrosine kinase in the ephrin receptor subfamily. EphA2 plays a role for angiogenesis and tumor neovascularization. High levels of EphA2 protein expression can be detected in some tumor cells such as breast carcinoma, bladder carcinoma, renal cell carcinoma (RCC), and non-small cell lung carcinoma (NSCLC). Inhibition of EphA2 kinase activity is considered for the treatment of various tumors such as RCC and NSCLC.

Immunogen

Synthetic peptide derived from the internal region of human EphA2 protein.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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