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  • SAB5500180 - Anti-Synaptophysin antibody, Rabbit monoclonal

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SAB5500180 Sigma-Aldrich

Anti-Synaptophysin antibody, Rabbit monoclonal

clone SP11, recombinant, expressed in proprietary host, tissue culture supernatant

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, Primary Antibodies, Rabbit Monoclonal Antibodies, Recombinant Rabbit Monoclonal Antibodies,
conjugate   unconjugated
clone   SP11, monoclonal
biological source   rabbit
application(s)   immunoblotting: 1:100
  immunohistochemistry: 1:200
species reactivity   human (tested)
species reactivity (predicted by homology)   bovine, mouse, rat
shipped in   wet ice
storage temp.   2-8°C
antibody form   tissue culture supernatant
isotype   IgG
Quality Level   100
recombinant   expressed in proprietary host
antibody product type   primary antibodies
UniProt accession no.   P08247
Gene Information   human ... SYP(6855)

Description

General description

This antibody recognizes a protein of 38kDa, identified as synaptophysin. It labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells in the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. Anti-synaptophysin antibody reacts with neuroendocrine neoplasms of neural as well as epithelial types e.g. neuroblastomas, ganglioneuroblastomas, ganglioneuromas, pheo-chromocytomas, chromaffin, and non-chromaffin paragangliomas.

Immunogen

Synthetic peptide corresponding to C-terminus of human synaptophysin.

Physical form

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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