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SAB5700004 Sigma-Aldrich

Anti-HDAC1 antibody produced in rabbit

Synonym: GON-10, HD1, HDAC1, RPD3, RPD3L1

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Properties

clone   polyclonal
biological source   rabbit
application(s)   immunofluorescence: 1:50-1:100
  immunohistochemistry: 1:100-1:200
  immunoprecipitation (IP): 1:50-1:100
  western blot: 1:500-1:2000
species reactivity   rat, human, mouse
mol wt   55 kDa
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
concentration   0.9 mg/ml
UniProt accession no.   Q13547
Gene Information   human ... HDAC1(3065)

Description

General description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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