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SAB5700046 Sigma-Aldrich

Anti-NF-kB p65 antibody produced in rabbit

Synonym: CMCU, NF-kB p65, NFKB3, RELA, p65

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Properties

clone   polyclonal
biological source   rabbit
application(s)   western blot: 1:500-1:1000
species reactivity   human, mouse
mol wt   58
  59
  60
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
concentration   0.97 mg/ml
UniProt accession no.   Q04206
Gene Information   human ... RELA(5970)

Description

General description

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human NF-kB p65 (NP_068810.3).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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