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SAB5700605 Sigma-Aldrich

Anti-MAPK3 antibody produced in rabbit

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Synonym: ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, MAPK3, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK

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Properties

clone   polyclonal
biological source   rabbit
application(s)   immunofluorescence: 1:50-1:200
  immunohistochemistry: 1:50-1:200
  western blot: 1:500-1:2000
species reactivity   rat, mouse, human
mol wt   38
  40
  43
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
concentration   0.32 mg/ml
UniProt accession no.   P27361
Gene Information   human ... MAPK3(5595)

Description

General description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPK3 (NP_002737.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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