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SAB5700625 Sigma-Aldrich

Anti-PPAR gamma antibody produced in rabbit

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Synonym: CIMT1, GLM1, NR1C3, PPAR gamma, PPARG1, PPARG2, PPARG, PPARgamma

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Properties

clone   polyclonal
biological source   rabbit
application(s)   immunofluorescence: 1:50-1:200
  immunohistochemistry: 1:50-1:200
  western blot: 1:500-1:2000
species reactivity   human, rat, mouse
mol wt   21
  54
  57
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
concentration   3.24 mg/ml
UniProt accession no.   P37231
Gene Information   human ... PPARG(5468)

Description

General description

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PPAR gamma (NP_056953.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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