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SAB5700745 Sigma-Aldrich

Anti-Survivin antibody produced in rabbit

Synonym: API4, BIRC5, EPR-1, Survivin

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Properties

clone   polyclonal
biological source   rabbit
application(s)   immunofluorescence: 1:50-1:200
  immunoprecipitation (IP): 1:50-1:100
  western blot: 1:500-1:2000
species reactivity   human, mouse, rat
mol wt   13
  15
  16
  18
  8
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   100
antibody product type   primary antibodies
concentration   1.70mg/ml
UniProt accession no.   O15392
Gene Information   human ... BIRC5(332)

Description

General description

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Survivin (NP_001159.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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