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SBR00020 Sigma-Aldrich

Zearalenone Ready Made Solution

1 mg/mL in DMSO

Synonym: (3S,11E)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-,1H-2-benzoxacyclotetradecin-1,7(8H)-dione, F-2 toxin

  • CAS Number 17924-92-4

  • Empirical Formula (Hill Notation) C18H22O5

  • Molecular Weight 318.36

  •  MDL number MFCD00133085

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Properties

Related Categories Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Chemopreventive Agents, Mold,
form   liquid
concentration   1 mg/mL in DMSO
storage temp.   −20°C
InChI   1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1
InChI key   MBMQEIFVQACCCH-QBODLPLBSA-N

Description

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium graminearum, binds estrogen receptor (ER) causing conformational alteration to the receptor. Zearalenone is a common contaminant in cereal grain used for animal and human food. It exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans. Furthermore, zearalenone was found to act as an immune-toxic compound, which can cause food consumption reduction in rats.

Safety & Documentation

Safety Information

WGK Germany 
WGK 2
Flash Point(F) 
188.6 °F - closed cup
Flash Point(C) 
87 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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