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SCP0095 Sigma-Aldrich

Caspase Inhibitor

≥95% (HPLC)

Synonym: Ac-LEHD-CHO, caspase 9 inhibitor

  • Empirical Formula (Hill Notation) C23H34N6O9

  • Molecular Weight 538.55

  •  NACRES NA.32

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Description

Amino Acid Sequence

Ac-Leu-Glu-His-Asp-al

Biochem/physiol Actions

Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9. Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3.

Safety & Documentation

Safety Information

WGK Germany 
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Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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