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SCP0168 Sigma-Aldrich

Histone Deacetylase Substrate

  • Empirical Formula (Hill Notation) C23H31N3O6

  • Molecular Weight 445.51

  •  NACRES NA.32

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Properties

assay   ≥95% (HPLC)
form   lyophilized
composition   Peptide Content, ≥85%
storage condition   protect from light
storage temp.   −20°C

Description

Amino Acid Sequence

BOC-Ac-Lys-AMC

Application

BOC-Ac-Lys-AMC (MAL) is used as a fluorogenic substrate for assaying both human zinc and NAD+-dependent histone deacetylases.

Safety & Documentation

Safety Information

WGK Germany 
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Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Histone Modification and Chromatin Remodeling

Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure. The primary protein components of chromatin are the his...
Savita Bagga, PhD.
BioFiles v7 n3, 2012, 10–16
Keywords: Acetylations, Amplification, Cancer, Cell culture, Chromatin immunoprecipitation, Cloning, DNA purification, Diseases, Epigenetics, Gene expression, Immunoprecipitation, Indicators, Methylations, Microarray Analysis, Polymerase chain reaction, Polymerase chain reaction - quantitative, Polymorphisms, Purification, Sequencing, Transcription, Whole genome amplification

Peer-Reviewed Papers
15

References

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