SHCLNG Sigma-Aldrich


Bacterial Stock

To order shRNA please search for your gene of interest.



Related Categories Functional Genomics and RNAi, MISSION shRNA, MISSION shRNA Gene Family Sets, Molecular Biology
Quality Level   200
shipped in   dry ice
storage temp.   −70°C


General description

Our comprehensive shRNA product offering consists of over 150,000 pre-cloned shRNA constructs targeting more than 15,000 human and 15,000 mouse genes. The library is available in: gene family sets: gene collections related to specific functional classes such as kinases and ion channels; gene taget sets, sets of shRNA clones that target your favorite gene; and individual shRNA clones. Our shRNA and lentiviral manufacturing platforms utilize dedicated laboratories featuring state-of-the-art robotics, liquid handling and laboratory information management systems (LIMS) to provide superior quality and service for your RNAi research needs.

MISSION® TRC shRNA bacterial glycerol stocks offer a renewable resource for shRNA plasmids. These plasmids can then be transfected directly, or packaged into lentiviral particles.


MISSION® shRNA has been used in the generation of damage-regulated autophagy modulator (DRAM) and p73 knockdown cell lines. It has also been used in lentivirus generation and gene knockdown and to investigate the contribution of PAX8 (paired box 8) in ovarian cancer progression.

Other Notes

To see protocols and application data please visit

Legal Information

Use of this product is subject to one or more license agreements.

MISSION is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

UN 3245 9
WGK Germany 


Certificate of Analysis (COA)

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Protocols & Articles

Related Content

MISSION® Lentiviral shRNA Technical Animation [VIDEO]

This video explains how MISSION RNAi (RNA interference) experiments leverage the natural RNAi mechanism. MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA th...
Keywords: Gene expression

shRNAs for Individual Genes

Our comprehensive shRNA product offering currently consists of almost 200,000 pre-cloned shRNA constructs targeting more than 22,500 human and 20,000 mouse genes. Each gene is represented by multiple...
Keywords: Cloning, Gene expression, PAGE, Transduction

Peer-Reviewed Papers


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Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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Need larger quantities for your development, manufacturing or research applications?