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SMB00292 Sigma-Aldrich

Fengycin

≥90%

Synonym: Fengycin, Plipastatin

  • Empirical Formula (Hill Notation) C72H110N12O20

  • Molecular Weight 1463.71

  •  NACRES NA.85

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics  A-F, Antifungal, Biochemicals and Reagents,
Quality Level   200
biological source   Bacillus subtilis
assay   ≥90%
form   powder
color   faintly yellow to light brown
Mode of action   cell membrane | interferes
antibiotic activity spectrum   fungi

Description

General description

Chemical structure: peptide

Fengycin is a lipopeptide complex which is synthesized by Bacillus subtilis strain F-29-3. It is an antifungal compound, and is made up of two components namely, fengycin A and fengycin B. Fengycin A contains 1 D-Ala, 1 L-Ile, 1 L-Pro, 1 D-allo-Thr, 3 L-Glx, 1 D-Tyr, 1 L-Tyr, 1 D-Orn, whereas fengycin B contains D-Val instead of D-Ala.

Application

Fengycin may be used for the sterilization of E. coli., and for the inactivation of spores of Bacillus cereus.

Biochem/physiol Actions

Fengycin shows antifungal properties against filamentous fungi, but has no action against yeast and bacteria. Certain unsaturated fatty acids facilitate the antifungal property, whereas sterols, phospholipids and oleic acid act as antagonists. It produces morphological abnormalities in fungi including curling, bulging and empyting of hyphae. Thus, it mainly functions through its effects on the plasma membrane.

Packaging

5MG

Storage and Stability

Store at 2 to 8 °C. (Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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