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SMB00611 Sigma-Aldrich

1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol sodium salt

≥98%

Synonym: 1,2-Didodecanoyl-sn-glycero-3-phosphorylglycerol sodium, 1-[[[(2,3-Dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester-dodecanoic acid sodium

  • CAS Number 73548-69-3

  • Empirical Formula (Hill Notation) C30H58O10PNa

  • Molecular Weight 632.74

  •  PubChem Substance ID 329825078

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Properties

Related Categories Biochemicals and Reagents, Glycerophosphoglycerols, Glycerophospholipids, Lipids
InChI Key   CIRSYGHBBDDURM-DUZWKJOOSA-M
assay   ≥98%
form   powder
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

100 mg in poly bottle

Biochem/physiol Actions

In nature, phosphatidylglycerol is a ubiquitous phospholipid that has specialized structural and functional properties in membranes. Although rare in mammalian membranes, it is highly prevalent in thylakoid membranes of cyanobacteria and higher plants, and it plays a role in photosynthesis. Phosphatidylglycerol may also have a role in bioactive sphingolipid signaling.

Phosphatidylglycerols are used in in silico studies of model membranes. Under specific experimental conditions, they exhibit similar phase transition properties as zwitterionic phosphatidylcholines. Lipid-based particle drug delivery studies using dispersions of dilauroylphosphatidylethanolamine (DLPE) and dilauroylphosphatidylglycerol (DLPG) have been shown to exhibit a metastable state which allows for the manipulation of delayed nucleation; thus providing new avenues in the design of novel modalities for the drug delivery of therapeutic payloads.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Webinar - Hydrogels
Protocols & Articles
Peer-Reviewed Papers
15

References

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